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Journal Article

Women undergoing primary total hip arthroplasty (THA) for hip fracture have lower in-hospital mortality compared to men.

Chandrupatla SR, Singh JA

Injury 55(12):111970 Dec 2024

Abstract

INTRODUCTION

We evaluated the association of patient sex with in-patient mortality and discharge disposition after primary total hip arthroplasty (THA) for hip fracture in the U.S.

METHODS

Using the 2016-2019 U.S. National Inpatient Sample (NIS), we calculated adjusted odds ratios (aOR) and 95% confidence intervals (CI) of the association of sex with post-procedural complications and in-hospital mortality after primary THA for hip fracture, adjusting for demographics, social determinants of health, medical comorbidity, hospital characteristics, and post-procedural complications.

RESULTS

There were 400,930 primary THA procedure hospitalizations for hip fracture in the 2016-2019 NIS data. In multivariable-adjusted analysis, compared to males, female sex was associated with lower in-hospital mortality following THA for hip fracture (aOR 0.65, 95 % CI 0.58 - 0.74; p < 0.001). Multivariable-adjusted analysis showed that female sex was associated with higher odds of discharge to a non-home destination after a THA for hip fracture (aOR 1.14, 95 % CI 1.07 - 1.22; p < 0.001).

CONCLUSIONS

Female sex was associated with lower in-hospital mortality after a THA for hip fracture. Further insights into the protective mechanisms that mediate this lower mortality in women undergoing a THA for hip fracture are needed to achieve better outcomes for men in the future.

Links & Identifiers

DOI
10.1016/j.injury.2024.111970 Open →
PubMed ID
39486394 View on PubMed →

MeSH Terms

  • Humans
  • Arthroplasty, Replacement, Hip
  • Female
  • Male
  • Hospital Mortality
  • Hip Fractures
  • Aged
  • Middle Aged
  • United States
  • Sex Factors
  • Aged, 80 and over
  • Postoperative Complications
  • Patient Discharge

Keywords

  • Death
  • Discharge
  • Epidemiology
  • Gender
  • Hip fracture
  • Mortality
  • Outcomes
  • Sex
  • Total hip arthroplasty

Citation

Chandrupatla SR, Singh JA. Women undergoing primary total hip arthroplasty (THA) for hip fracture have lower in-hospital mortality compared to men.. Injury. 2024;55(12):111970. doi: 10.1016/j.injury.2024.111970

BibTeX

@article{sr2024womenundergoingprimary,
  title = {Women undergoing primary total hip arthroplasty (THA) for hip fracture have lower in-hospital mortality compared to men.},
  author = {Chandrupatla SR and Singh JA},
  journal = {Injury},
  year = {2024},
  volume = {55},
  number = {12},
  pages = {111970},
  doi = {10.1016/j.injury.2024.111970},
  pmid = {39486394},
  url = {https://doi.org/10.1016/j.injury.2024.111970}
}